Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 9/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.51 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884208 | 0.88 | PIK3CG (0.73) | PIK3CGPIK3CDABL1SRCPIK3CA | |
| SCHEMBL21769532 | 0.85 | PIK3CD (0.64) | PIK3CGPIK3CDABL1SRCPIK3CA | |
| SCHEMBL9884120 | 0.84 | PIK3CD (0.78) | PIK3CGPIK3CDABL1SRCPIK3CA | |
| SCHEMBL9884199 | 0.82 | PIK3CD (0.67) | PIK3CGPIK3CDABL1SRCPIK3CA | |
| SCHEMBL9884074 | 0.82 | PIK3CG (0.83) | PIK3CGPIK3CDABL1SRCPIK3CA | |
| SCHEMBL9884209 | 0.80 | PIK3CD (0.82) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C2B | |
| SCHEMBL18708417 | 0.80 | PIK3CG (0.75) | PIK3CGPIK3CDABL1SRCPIK3CA | |
| SCHEMBL20725975 | 0.80 | PIK3CG (0.75) | PIK3CGPIK3CDABL1SRCPIK3CA | |
| SCHEMBL19935751 | 0.79 | PIK3CD (0.60) | PIK3CGPIK3CDABL1SRCPIK3CA | |
| SCHEMBL9884211 | 0.78 | PIK3CD (0.71) | PIK3CGPIK3CDABL1SRCPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613743-A1 | PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES | Intellikine, LLC (US) | 2020-02-26 | — | — | EP | disclosed |