SCHEMBL21769778

SCHEMBL21769778

c1ccc(-c2c3ccccc3c(-c3ccc(-c4cccc(-c5nc6ccccc6n5-c5ccccc5)c4)cc3)c3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
HDAC1 Q13547 3/20 0.50
HDAC8 Q9BY41 3/20 0.50
HDAC6 Q9UBN7 3/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPT P10636 2/20 0.47
HSP90AA1 P07900 1/20 0.47
HTT P42858 2/20 0.47
MAPK1 P28482 1/20 0.47
GRIA1 P42261 1/20 0.46
CACNG8 Q8WXS5 1/20 0.46
CACNG2 Q9Y698 1/20 0.46
GAA P10253 2/20 0.45
PTGER4 P35408 1/20 0.45
RECQL P46063 1/20 0.44
PRKACA P17612 1/20 0.43
RPS6KB1 P23443 1/20 0.43
GSK3B P49841 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14363289 0.97 ESR2 (0.57) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL25769073 0.97 ESR2 (0.57) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL26343636 0.97 ESR1 (0.53) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL25668036 0.96 ESR1 (0.56) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL14000274 0.96 ESR2 (0.56) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL26343739 0.96 ESR1 (0.55) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL26345247 0.95 ESR1 (0.49) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL14000373 0.95 ESR1 (0.48) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL12887915 0.95 ESR1 (0.51) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL18999481 0.95 ESR1 (0.56) ESR1ESR2HDAC1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020040434-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-27 WO disclosed