Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 20/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21770821 | 0.81 | CACNA2D1 (0.51) | CACNA2D1SLC6A2 | |
| SCHEMBL21770905 | 0.81 | CACNA2D1 (0.52) | CACNA2D1SLC6A2 | |
| SCHEMBL21770324 | 0.80 | CACNA2D1 (0.51) | CACNA2D1SLC6A2 | |
| SCHEMBL21770822 | 0.77 | CACNA2D1 (0.52) | CACNA2D1SLC6A2 | |
| SCHEMBL20932817 | 0.74 | CACNA2D1 (0.53) | CACNA2D1SLC6A2 | |
| SCHEMBL21770556 | 0.72 | CACNA2D1 (0.51) | CACNA2D1SLC6A2 | |
| SCHEMBL30438241 | 0.69 | CACNA2D1 (0.49) | CACNA2D1SLC6A2 | |
| SCHEMBL20917084 | 0.69 | CACNA2D1 (0.49) | CACNA2D1SLC6A2 | |
| SCHEMBL30439006 | 0.68 | CACNA2D1 (0.57) | CACNA2D1SLC6A2 | |
| SCHEMBL20917066 | 0.68 | CACNA2D1 (0.51) | CACNA2D1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452475-B1 | TETRAHYDROPYRIMIDODIAZEPINE AND TETRAHYDROPYRIDODIAZEPINE COMPOUNDS FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS SA (ES) | 2020-02-26 | — | — | EP | disclosed |