SCHEMBL2177303

SCHEMBL2177303

CC(=O)CN[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
ALOX15 P16050 2/20 0.45
BLM P54132 2/20 0.45
PMP22 Q01453 1/20 0.45
MMP2 P08253 2/20 0.41
MMP9 P14780 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CA2 P00918 5/20 0.40
CA1 P00915 4/20 0.40
FOLH1 Q04609 4/20 0.38
RIMKLA Q8IXN7 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.38
GGH Q92820 1/20 0.37
BMP1 P13497 1/20 0.36
GGT1 P19440 1/20 0.36
NOD1 Q9Y239 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
NFKB1 P19838 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28142279 1.00 KMT2A (0.45) KMT2AALOX15BLMPMP22MMP2
SCHEMBL21802287 0.86 KMT2A (0.47) KMT2AALOX15BLMPMP22MMP2
SCHEMBL6554061 0.86 KMT2A (0.47) KMT2AALOX15BLMPMP22MMP2
SCHEMBL8768913 0.84 KMT2A (0.48) KMT2AALOX15BLMPMP22MMP2
SCHEMBL8768917 0.84 KMT2A (0.48) KMT2AALOX15BLMPMP22MMP2
SCHEMBL23824889 0.84 FOLH1 (0.41) KMT2AALOX15BLMPMP22MMP2
SCHEMBL4292884 0.83 KMT2A (0.44) KMT2AALOX15BLMPMP22MMP2
SCHEMBL4397483 0.83 KMT2A (0.44) KMT2AALOX15BLMPMP22MMP2
SCHEMBL516528 0.82 KMT2A (0.47) KMT2AALOX15BLMPMP22MMP2
SCHEMBL516527 0.82 KMT2A (0.47) KMT2AALOX15BLMPMP22MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7196065-B2 Enteral formulation ERNEST STEPHEN P 2007-03-27 US claimed
US-20050070498-A1 Enteral formulation ERNEST STEPHEN P (US) 2005-03-31 US claimed
US-6221836-B1 Composition of pyruvate and anabolic protein and method for increasing fat loss in a mammal PAXTON KING BEALE 2001-04-24 US claimed
US-6008252-A Method for increasing muscle mass in a mammal BEALE PAXTON K (US) 1999-12-28 US claimed
EP-2493467-B1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS HILLS PET NUTRITION INC (US) 2017-05-31 EP disclosed
EP-2519115-B1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF HILLS PET NUTRITION INC (US) 2017-02-15 EP disclosed
US-9173422-B2 Compositions including pyruvate for companion animals and methods of use thereof HILL'S PET NUTRITION, INC. (US) 2015-11-03 US disclosed
US-9011900-B2 Compositions including pyruvate for companion animals and methods of use thereof HILL'S PET NUTRITION, INC. (US) 2015-04-21 US disclosed
US-8999375-B2 Compositions including pyruvate for companion animals and methods of use thereof HILL'S PET NUTRITION, INC. (US) 2015-04-07 US disclosed
US-20120309829-A1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF HILL'S PET NUTRITION, INC. (US) 2012-12-06 US disclosed
US-20120309828-A1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF HILL'S PET NUTRITION, INC. (US) 2012-12-06 US disclosed
US-20120289598-A1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF HILL'S PET NUTRITION, INC. (US) 2012-11-15 US disclosed
EP-2519115-A1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF Hill's Pet Nutrition, Inc. (US) 2012-11-07 EP disclosed
EP-2493467-A1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF Hill's Pet Nutrition, Inc. (US) 2012-09-05 EP disclosed
WO-2011090676-A1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF HILL'S PET NUTRITION, INC. (US) 2011-07-28 WO disclosed
WO-2011082080-A1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF HILL'S PET NUTRITION, INC. (US) 2011-07-07 WO disclosed
WO-2011082081-A1 COMPOSITIONS INCLUDING PYRUVATE FOR COMPANION ANIMALS AND METHODS OF USE THEREOF HILL'S PET NUTRITION, INC. (US) 2011-07-07 WO disclosed
US-20050129835-A1 High protein content food supplement DELAHANTY DONALD W JR (US) 2005-06-16 US disclosed
US-6221836-B1 Composition of pyruvate and anabolic protein and method for increasing fat loss in a mammal PAXTON KING BEALE 2001-04-24 US disclosed
US-6008252-A Method for increasing muscle mass in a mammal BEALE PAXTON K (US) 1999-12-28 US disclosed