⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28026074 | 0.91 | — | — | |
| SCHEMBL406 | 0.89 | — | — | |
| SCHEMBL28609030 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL21831870 | 0.80 | — | — | |
| SCHEMBL28509021 | 0.80 | — | — | |
| SCHEMBL20549069 | 0.80 | — | — | |
| SCHEMBL22129292 | 0.80 | — | — | |
| SCHEMBL22129839 | 0.80 | — | — | |
| SCHEMBL20857704 | 0.80 | — | — | |
| SCHEMBL20657776 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3843733-A1 | PROCESSES FOR PREPARING A MDM2 INHIBITOR | Amgen Inc. (US) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020047424-A1 | PROCESSES FOR PREPARING A MDM2 INHIBITOR | AMGEN, INC. (US) | 2020-03-05 | — | — | WO | disclosed |
| CN-105838505-A | Kitchen oil-removing foams for removing heavy-oil contaminations | 杭州氧泡泡生物科技有限公司 | 2016-08-10 | — | — | CN | disclosed |