Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 13/20 | 0.44 |
| ▸ | GBA1 | P04062 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | UGCG | Q16739 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 2/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28981624 | 0.83 | GBA2 (0.42) | GBA2GBA1GAAUGCGGUSB | |
| SCHEMBL4893528 | 0.83 | GBA2 (0.54) | GBA2GBA1GAAUGCG | |
| SCHEMBL10940184 | 0.83 | GBA2 (0.42) | GBA2GBA1GAAUGCGGUSB | |
| SCHEMBL4892211 | 0.83 | GBA2 (0.54) | GBA2GBA1GAAUGCG | |
| SCHEMBL4885572 | 0.83 | GBA2 (0.54) | GBA2GBA1GAAUGCG | |
| SCHEMBL5691697 | 0.76 | EBP (0.52) | GBA2GBA1GAAUGCGGUSB | |
| SCHEMBL28479251 | 0.76 | EBP (0.52) | GBA2GBA1GAAUGCGGUSB | |
| SCHEMBL28813835 | 0.76 | EBP (0.52) | GBA2GBA1GAAUGCGGUSB | |
| SCHEMBL28489520 | 0.76 | EBP (0.52) | GBA2GBA1GAAUGCGGUSB | |
| SCHEMBL8459951 | 0.76 | EBP (0.52) | GBA2GBA1GAAUGCGGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10578624-B2 | Determination of glycosaminoglycan levels by mass spectrometry | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2020-03-03 | — | — | US | disclosed |