⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15258081 | 1.00 | — | — | |
| SCHEMBL15922701 | 0.78 | HTT (0.30) | — | |
| SCHEMBL22024144 | 0.77 | ATM (0.30) | — | |
| SCHEMBL14966029 | 0.77 | POLB (0.32) | — | |
| SCHEMBL19261669 | 0.75 | — | — | |
| SCHEMBL15832392 | 0.74 | ADORA2A (0.30) | — | |
| SCHEMBL18776516 | 0.74 | ADORA2A (0.30) | — | |
| SCHEMBL25545267 | 0.74 | ADORA2A (0.30) | — | |
| SCHEMBL15259372 | 0.74 | ADORA2A (0.30) | — | |
| SCHEMBL25559107 | 0.74 | ADORA2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577378-B2 | EIF4A-inhibiting compounds and methods related thereto | EFFECTOR THERAPEUTICS, INC. (US) | 2020-03-03 | — | — | US | disclosed |