Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17008511 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2A13ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3832305 | 0.87 | — | — | |
| SCHEMBL14862483 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2A13ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL26008055 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL2950437 | 0.85 | — | — | |
| SCHEMBL14529673 | 0.85 | KDM2B (0.36) | SMN1; SMN2ALDH1A1L3MBTL1L3MBTL3HRH3 | |
| SCHEMBL15552632 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2A13ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL2115253 | 0.83 | — | — | |
| SCHEMBL13558432 | 0.83 | — | — | |
| SCHEMBL12065889 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344613-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |