Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25593983 | 0.86 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL6275609 | 0.82 | EPHX1 (0.35) | EPHX1 | |
| SCHEMBL16287226 | 0.80 | TSHR (0.33) | — | |
| SCHEMBL6270852 | 0.79 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL24593051 | 0.77 | — | — | |
| SCHEMBL19853518 | 0.76 | — | — | |
| SCHEMBL9248668 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL597579 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL10039386 | 0.72 | EPHX1 (0.35) | EPHX1 | |
| SCHEMBL22031411 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484856-B1 | 2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS | REVOLUTION MEDICINES INC (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2020102004-A2 | HYDROLYTICALLY STABLE POLYMERS, METHOD OF SYNTHESIS THEREOF AND USE IN BIO-ELECTRONIC DEVICES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-05-22 | — | — | WO | disclosed |
| EP-3617235-A1 | COMPOUND HAVING SUBSTANCE THAT HAS AFFINITY FOR SOLUBLE PROTEIN, CLEAVABLE MOIETY, AND REACTIVE GROUP, OR SALT THEREOF | Ajinomoto Co., Inc. (JP) | 2020-03-04 | — | — | EP | disclosed |