Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12259239 | 0.85 | HRH3 (0.47) | DPP4DPP8HRH3VNN1KCNH2 | |
| SCHEMBL26885381 | 0.85 | HRH3 (0.47) | DPP4DPP8HRH3VNN1KCNH2 | |
| SCHEMBL13934309 | 0.85 | HRH3 (0.47) | DPP4DPP8HRH3VNN1KCNH2 | |
| SCHEMBL26450845 | 0.82 | HRH3 (0.40) | DPP4DPP8HRH3VNN1KCNH2 | |
| SCHEMBL13212810 | 0.80 | DPP4 (0.43) | DPP4DPP8HRH3VNN1KCNH2 | |
| SCHEMBL23323871 | 0.79 | HRH3 (0.32) | HRH3 | |
| SCHEMBL23023309 | 0.77 | HRH3 (0.34) | HRH3 | |
| SCHEMBL23023301 | 0.77 | HRH3 (0.32) | DPP4HRH3DPP9 | |
| SCHEMBL20314944 | 0.77 | JAK3 (0.39) | HRH3 | |
| SCHEMBL25909029 | 0.76 | HRH3 (0.34) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3616753-A1 | COMPOUNDS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |