Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779876 | 1.00 | HRH3 (0.43) | HRH3DRD2DRD3 | |
| SCHEMBL13101427 | 0.88 | HRH3 (0.49) | HRH3 | |
| SCHEMBL12801526 | 0.84 | HRH3 (0.34) | HRH3 | |
| SCHEMBL16279294 | 0.83 | HRH3 (0.44) | HRH3 | |
| SCHEMBL15018879 | 0.83 | HRH3 (0.44) | HRH3 | |
| SCHEMBL19710796 | 0.81 | HRH3 (0.33) | HRH3 | |
| SCHEMBL9963119 | 0.79 | HRH3 (0.38) | HRH3 | |
| SCHEMBL8121510 | 0.79 | HRH3 (0.38) | HRH3 | |
| SCHEMBL9963118 | 0.79 | HRH3 (0.38) | HRH3 | |
| SCHEMBL24167623 | 0.79 | HRH3 (0.31) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257828-A1 | SUBSTITUTED THIENOPYRIMIDINES THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2021-12-23 | — | — | WO | disclosed |
| EP-3616753-A1 | COMPOUNDS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |