Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 7/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767756 | 1.00 | KDM1A (0.39) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL31071952 | 1.00 | KDM1A (0.39) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL28247206 | 0.84 | KDM1A (0.37) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL21780606 | 0.74 | HTR2B (0.37) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL28841128 | 0.73 | HTR2B (0.38) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL10300817 | 0.70 | HTR2C (0.47) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL7440746 | 0.70 | HTR2C (0.47) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL30036946 | 0.70 | HTR2C (0.47) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL2177894 | 0.69 | HTR2C (0.40) | KDM1ARCOR1HTR2BHTR2CHTR2A | |
| SCHEMBL15741269 | 0.69 | HTR2C (0.40) | KDM1AHTR2BHTR2CHTR2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617206-A1 | INTEGRIN INHIBITORS | Morphic Therapeutic, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |