Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15883513 | 1.00 | TLR8 (0.32) | TLR8 | |
| SCHEMBL15883461 | 1.00 | TLR8 (0.32) | TLR8 | |
| SCHEMBL22138679 | 1.00 | TLR8 (0.32) | TLR8 | |
| SCHEMBL12791608 | 1.00 | TLR8 (0.32) | TLR8 | |
| SCHEMBL22421789 | 0.84 | CCR6 (0.32) | — | |
| SCHEMBL15038210 | 0.78 | — | — | |
| SCHEMBL25235209 | 0.75 | — | — | |
| SCHEMBL20790445 | 0.75 | — | — | |
| SCHEMBL19381698 | 0.75 | — | — | |
| SCHEMBL16384327 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945939-B1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE HOLDINGS CORP (US) | 2020-03-04 | — | — | EP | disclosed |