Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22068461 | 0.90 | NAMPT (0.48) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL22068087 | 0.88 | MAPT (0.47) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL8245694 | 0.83 | CYP17A1 (0.54) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL21138222 | 0.83 | NAMPT (0.50) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL21137676 | 0.83 | NAMPT (0.50) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL21781781 | 0.83 | NAMPT (0.50) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL21781780 | 0.82 | NAMPT (0.47) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL16523129 | 0.82 | CYP17A1 (0.56) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL21781875 | 0.81 | CYP17A1 (0.52) | NAMPTCYP17A1AURKARPS6KB1HDAC1 | |
| SCHEMBL21768217 | 0.80 | NPC1 (0.51) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207420-B2 | Cytotoxin and conjugate, uses of same and preparation method therefor | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200179529-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME AND PREPARATION METHOD THEREFOR | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |
| CN-110312730-A | Cytotoxin and conjugate, its Use and preparation method | 四川科伦博泰生物医药股份有限公司 | 2019-10-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11207420-B2 | Cytotoxin and conjugate, uses of same and preparation method therefor | CD2, HAVCR2, CD4 | NAMPT 4254/4885CYP17A1 3494/4885CARM1 1474/4885 |
| US-20200179529-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME AND PREPARATION METHOD THEREFOR | CD2, HAVCR2, CD4 | NAMPT 4254/4885CYP17A1 3494/4885CARM1 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.