Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 17/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18126623 | 0.89 | OXER1 (0.77) | OXER1ACLY | |
| SCHEMBL21782187 | 0.87 | OXER1 (0.71) | OXER1 | |
| SCHEMBL21781996 | 0.87 | OXER1 (0.77) | OXER1TBXAS1 | |
| SCHEMBL21782028 | 0.84 | OXER1 (0.69) | OXER1TBXAS1 | |
| SCHEMBL21782153 | 0.83 | OXER1 (0.66) | OXER1 | |
| SCHEMBL21782203 | 0.82 | OXER1 (0.68) | OXER1 | |
| SCHEMBL18126565 | 0.76 | OXER1 (0.76) | OXER1 | |
| SCHEMBL18126596 | 0.76 | OXER1 (0.76) | OXER1 | |
| SCHEMBL18126593 | 0.76 | OXER1 (0.76) | OXER1 | |
| SCHEMBL18112951 | 0.76 | OXER1 (0.76) | OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277665-B1 | INDOLE ANALOGS AS 5-OXO-ETE RECEPTOR ANTAGONISTS AND METHOD OF USE THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2020-03-04 | — | — | EP | disclosed |