Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21781779 | 0.87 | CYP3A4 (0.42) | CYP3A4FOLH1AKT1TTRITGB1 | |
| SCHEMBL21782123 | 0.87 | CYP3A4 (0.45) | CYP3A4FOLH1AKT1TTRITGB1 | |
| SCHEMBL21781954 | 0.86 | CYP3A4 (0.44) | CYP3A4FOLH1AKT1TTRSSTR2 | |
| SCHEMBL21781773 | 0.83 | CYP3A4 (0.45) | CYP3A4FOLH1AKT1TTRSSTR2 | |
| SCHEMBL21781950 | 0.83 | CYP3A4 (0.46) | CYP3A4FOLH1AKT1TTRSSTR2 | |
| SCHEMBL24136561 | 0.82 | CYP3A4 (0.46) | CYP3A4FOLH1AKT1TTRSSTR2 | |
| SCHEMBL21781872 | 0.82 | CYP3A4 (0.46) | CYP3A4FOLH1AKT1TTRSSTR2 | |
| SCHEMBL21781961 | 0.82 | CYP3A4 (0.46) | CYP3A4FOLH1AKT1TTRSSTR2 | |
| SCHEMBL21781997 | 0.82 | CYP3A4 (0.45) | CYP3A4FOLH1AKT1TTRSSTR2 | |
| SCHEMBL24136571 | 0.80 | CYP3A4 (0.46) | CYP3A4FOLH1AKT1TTRSSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |