Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037624 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AMAPTNPC1GAA | |
| SCHEMBL19151154 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2TP53RAB9AMAPTNPC1 | |
| SCHEMBL22540339 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2TP53RAB9AMAPTNPC1 | |
| SCHEMBL1428750 | 0.81 | MAPT (0.65) | SMN1; SMN2RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL18653618 | 0.81 | NPSR1 (0.50) | SMN1; SMN2MAPTLMNAKDM4ECA1 | |
| SCHEMBL4531127 | 0.80 | MAPT (0.68) | SMN1; SMN2RAB9AMAPTNPC1GAA | |
| SCHEMBL18653619 | 0.80 | CA1 (0.50) | SMN1; SMN2RAB9AMAPTNPC1GAA | |
| SCHEMBL19002813 | 0.80 | MEN1 (0.71) | SMN1; SMN2TP53RAB9AMAPTNPC1 | |
| SCHEMBL19154287 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2TP53RAB9AMAPTNPC1 | |
| SCHEMBL19116341 | 0.79 | PTPN1 (0.67) | SMN1; SMN2RAB9AMAPTNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402783-B1 | 3-(CARBOXYETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-03-04 | — | — | EP | disclosed |