Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 10/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21074643 | 0.94 | MEN1 (0.65) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL21074712 | 0.81 | MEN1 (0.67) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL21074751 | 0.81 | KDM4E (0.58) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL21074635 | 0.79 | POLB (0.54) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL21074775 | 0.78 | MEN1 (0.65) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL10584006 | 0.78 | MEN1 (0.86) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL10584011 | 0.78 | MEN1 (0.86) | MEN1KMT2AKCNH2POLBCACNA1F | |
| Orbifloxacin SCHEMBL29420860 | 0.77 | MEN1 (1.00) | MEN1KMT2AKCNH2POLBCACNA1F | |
| Orbifloxacin SCHEMBL9374152 | 0.77 | MEN1 (1.00) | MEN1KMT2AKCNH2POLBCACNA1F | |
| Orbifloxacin SCHEMBL125116 | 0.77 | MEN1 (1.00) | MEN1KMT2AKCNH2POLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |