Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21074770 | 0.89 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL21074765 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL21783179 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL21074624 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL21783154 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL21074744 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL21783231 | 0.74 | KDM4E (0.40) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL30306078 | 0.74 | KDM4E (0.77) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5006578 | 0.74 | KDM4E (0.77) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL23197395 | 0.73 | PIK3CG (0.57) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |