Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783237 | 0.86 | KDM4E (0.60) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL21783174 | 0.80 | KDM4E (0.53) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL21783205 | 0.77 | KDM4E (0.60) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL21783282 | 0.76 | KDM4E (0.43) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL21074743 | 0.76 | KDM4E (0.52) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL21783283 | 0.75 | KDM4E (0.62) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL14010098 | 0.74 | KDM4E (0.58) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL28416357 | 0.74 | KDM4E (0.80) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL14010099 | 0.74 | KDM4E (0.64) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL16011449 | 0.74 | KDM4E (0.82) | KDM4EHPGDALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |