Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 3/20 | 0.69 |
| ▸ | MLNR | O43193 | 1/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.69 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | CCKAR | P32238 | 1/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | GHSR | Q92847 | 1/20 | 0.69 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.69 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 10/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 10/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 10/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 10/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 10/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018952 | 0.97 | UGT1A1 (0.71) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL2175950 | 0.97 | UGT1A1 (0.71) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL8162986 | 0.97 | UGT1A1 (0.71) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL1300966 | 0.97 | UGT1A1 (0.71) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL10034686 | 0.94 | UGT1A1 (0.69) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL16298849 | 0.94 | UGT1A1 (0.73) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL8224259 | 0.92 | UGT1A1 (0.66) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL893599 | 0.91 | UGT1A1 (0.67) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL17635632 | 0.90 | UGT1A1 (0.71) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL16866221 | 0.90 | UGT1A1 (0.67) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080562-A1 | NOVEL AZA-PEPTIDES CONTAINING 2,2-DISUBSTITUTED CYCLOBUTYL AND/OR SUBSTITUTED ALKOXY BENZYL DERIVATIVES AS ANTIVIRALS | HETERO RESEARCH FOUNDATION (IN) | 2011-07-07 | — | — | WO | disclosed |