Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 16/20 | 0.43 |
| ▸ | SCN1A | P35498 | 15/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 13/20 | 0.43 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20256235 | 0.79 | SCN8A (0.44) | SCN8ASCN1ASCN5ASCN1B | |
| SCHEMBL20256531 | 0.78 | SCN8A (0.55) | SCN8ASCN1ASCN5ASCN1B | |
| SCHEMBL21783448 | 0.78 | SCN8A (0.42) | SCN8ASCN1ASCN5ASCN1BMEN1 | |
| SCHEMBL20256344 | 0.76 | SCN8A (0.46) | SCN8ASCN1ASCN5ASCN1B | |
| SCHEMBL21783347 | 0.76 | SCN8A (0.70) | SCN8ASCN1ASCN5ASCN1BSCN9A | |
| SCHEMBL19634111 | 0.75 | SCN1A (0.36) | SCN8ASCN1ASCN5ASCN1BSCN9A | |
| SCHEMBL20256587 | 0.71 | SCN8A (0.64) | SCN8ASCN1ASCN5ASCN1BMEN1 | |
| SCHEMBL20256638 | 0.71 | SCN1A (0.43) | SCN8ASCN1ASCN5ASCN1BSCN9A | |
| SCHEMBL20256323 | 0.70 | SCN8A (0.52) | SCN8ASCN1ASCN5ASCN1B | |
| SCHEMBL20256743 | 0.69 | SCN8A (0.49) | SCN8ASCN1ASCN5ASCN1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047323-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |