⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199619 | 0.71 | — | — | |
| SCHEMBL18601879 | 0.69 | — | — | |
| SCHEMBL3828079 | 0.69 | — | — | |
| SCHEMBL11247604 | 0.66 | — | — | |
| SCHEMBL24212169 | 0.66 | MAPT (0.31) | — | |
| SCHEMBL29340433 | 0.66 | — | — | |
| SCHEMBL19479314 | 0.64 | — | — | |
| SCHEMBL28363213 | 0.59 | — | — | |
| SCHEMBL23225948 | 0.58 | — | — | |
| SCHEMBL14652761 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043173-A1 | HETEROCYCLIC COMPOUND AS RECEPTOR INTERACTING PROTEIN 1(RIP1) KINASE INHIBITOR | 宁波文达医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |