Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 9/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328284 | 0.86 | FGFR1 (0.39) | FGFR1FGFR4KDR | |
| SCHEMBL29545548 | 0.81 | FGFR2 (0.52) | FGFR1FGFR2FGFR4 | |
| SCHEMBL20733977 | 0.81 | FGFR2 (0.52) | FGFR1FGFR2FGFR4 | |
| SCHEMBL23328281 | 0.78 | FGFR1 (0.54) | FGFR1FGFR2FGFR4KDR | |
| SCHEMBL21783930 | 0.77 | FGFR1 (0.57) | FGFR1FGFR4KDR | |
| SCHEMBL23328264 | 0.77 | FGFR1 (0.42) | FGFR1FGFR4KDR | |
| SCHEMBL23328261 | 0.76 | FGFR1 (0.42) | FGFR1FGFR4KDR | |
| SCHEMBL23328714 | 0.74 | FGFR1 (0.39) | FGFR1FGFR2FGFR4KDR | |
| SCHEMBL21783951 | 0.74 | MEN1 (0.36) | FGFR1FGFR2FGFR4KDR | |
| SCHEMBL21783949 | 0.72 | FGFR1 (0.47) | FGFR1FGFR4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043078-A1 | SALT FORM AND CRYSTAL FORM OF NOVEL AZATRICYCLIC COMPOUND AND USE THEREOF | 贝达药业股份有限公司 | 2020-03-05 | — | — | WO | disclosed |