SCHEMBL21784191

SCHEMBL21784191

CCCC(C)(C)c1noc(C(C)(C)C)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21784146 0.85 PIK3CG (0.36) PIK3CG
SCHEMBL21784145 0.84 PIK3CG (0.31) PIK3CG
SCHEMBL15691300 0.83
SCHEMBL78067 0.77 PIK3CG (0.43) PIK3CG
SCHEMBL22545665 0.75
SCHEMBL21233393 0.74 PIK3CG (0.30) PIK3CG
SCHEMBL15483338 0.74 PIK3CG (0.30) PIK3CG
SCHEMBL22854005 0.74 PIK3CG (0.39) PIK3CG
SCHEMBL15483312 0.72 PIK3CG (0.38) PIK3CG
SCHEMBL23554259 0.72 PIK3CG (0.33) PIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4218752-A1 MARKER FOR DETERMINING ANTI-CANCER EFFECTS OF MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION PATHWAY INHIBITOR Nanjing Shijiang Medicine Technology Co., Ltd (CN) 2023-08-02 EP disclosed
US-20200071327-A1 Prodrugs for the Treatment of Disease OPPILAN PHARMA LTD (GB) 2020-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200071327-A1 Prodrugs for the Treatment of Disease DPYD, PAICS, TYMP PIK3CG 1828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.