SCHEMBL21784385

SCHEMBL21784385

CC(C)(C)OC(=O)NS(=O)(=O)N1CC(CC#N)(N2CCC(NC3CC3c3ccccc3)CC2)C1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21788630 1.00 KDM1A (0.73) KDM1A
SCHEMBL21784461 1.00 KDM1A (0.73) KDM1A
SCHEMBL21784346 1.00 KDM1A (0.73) KDM1A
SCHEMBL21775421 0.88 KDM1A (0.57) KDM1A
SCHEMBL16989443 0.85 KDM1A (0.83) KDM1A
SCHEMBL16989441 0.85 KDM1A (0.83) KDM1A
SCHEMBL16995855 0.85 KDM1A (0.83) KDM1A
SCHEMBL22922935 0.85 KDM1A (1.00) KDM1A
SCHEMBL16989535 0.85 KDM1A (1.00) KDM1A
SCHEMBL16995789 0.85 KDM1A (1.00) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210300891-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME INCYTE CORPORATION 2021-09-30 US disclosed
US-10968200-B2 Salts of an LSD1 inhibitor and processes for preparing the same INCYTE CORPORATION (US) 2021-04-06 US disclosed
WO-2020047198-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME INCYTE CORPORATION (US) 2020-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210300891-A1 SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME KDM1A, KDM1B, KDM2A KDM1A 1/4885
US-10968200-B2 Salts of an LSD1 inhibitor and processes for preparing the same KDM1A, KDM1B, KDM2A KDM1A 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.