Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21784825 | 0.84 | ORAI1 (0.42) | ORAI1PDE7AKMT2AMEN1POLB | |
| SCHEMBL26266194 | 0.82 | ORAI1 (0.47) | ORAI1PDE7APTGESKMT2AMEN1 | |
| SCHEMBL5186081 | 0.80 | ORAI1 (0.43) | ORAI1PDE7AKMT2AMEN1HSP90AA1 | |
| SCHEMBL24390457 | 0.80 | KMT2A (0.44) | ORAI1PDE7APTGESKMT2AMEN1 | |
| SCHEMBL21784548 | 0.79 | CYP1A1 (0.53) | ORAI1PDE7APTGESKMT2AMEN1 | |
| SCHEMBL22177425 | 0.78 | HSP90AA1 (0.41) | ORAI1PTGESKMT2AMEN1POLB | |
| SCHEMBL26536556 | 0.77 | ORAI1 (0.44) | ORAI1PDE7APTGESKMT2AMEN1 | |
| SCHEMBL19802964 | 0.77 | POLB (0.38) | ORAI1PTGESKMT2AMEN1POLB | |
| SCHEMBL20321846 | 0.76 | NPC1 (0.45) | ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL21784550 | 0.75 | EGFR (0.44) | ORAI1PDE7APTGESKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220109115-A1 | POLYCYCLIC COMPOUND, AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND | IDEMITSU KOSAN CO.,LTD. (JP) | 2022-04-07 | — | — | US | disclosed |
| WO-2020044270-A1 | POLYCYCLIC COMPOUND, AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220109115-A1 | POLYCYCLIC COMPOUND, AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND | ODC1, OTC, PKD1 | ORAI1 401/4885PDE7A 4394/4885PTGES 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.