SCHEMBL21786

SCHEMBL21786

O=C(Cl)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.64
SRD5A2 P31213 5/20 0.62
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
LTA4H P09960 2/20 0.52
TSHR P16473 1/20 0.52
NR1H2 P55055 1/20 0.52
BAX Q07812 1/20 0.52
AKR1C3 P42330 1/20 0.52
PGR P06401 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 1/20 0.50
PARP15 Q460N3 1/20 0.50
PARP14 Q460N5 1/20 0.50
PARP16 Q8N5Y8 1/20 0.50
PARP11 Q9NR21 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
KCNQ3 O43525 1/20 0.50
KCNQ2 O43526 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249310 1.00 PARP10 (0.64) PARP10SRD5A2ERCC5FEN1LTA4H
Diphenylether SCHEMBL9717017 0.98 PARP10 (0.61) PARP10SRD5A2ERCC5FEN1LTA4H
Hydrochloric Acid SCHEMBL10411245 0.96 PARP10 (0.60) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL9402135 0.94 SRD5A2 (0.72) PARP10SRD5A2ERCC5FEN1PGR
Hydrochloric Acid SCHEMBL10805398 0.94 PARP10 (0.58) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL9186446 0.94 PARP10 (0.58) PARP10SRD5A2ERCC5FEN1LTA4H
SCHEMBL9185644 0.94 SRD5A2 (0.72) PARP10SRD5A2ERCC5FEN1PGR
1,2-Dichloroethane SCHEMBL9413693 0.92 PARP10 (0.56) PARP10SRD5A2ERCC5FEN1PGR
SCHEMBL272345 0.91 PARP10 (0.58) PARP10SRD5A2TSHRSMN1; SMN2ALDH1A1
SCHEMBL9786679 0.91 PARP10 (0.58) PARP10SRD5A2TSHRSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 619 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080343-A Method for synthesizing polyarylketone compound 2026-05-26 CN claimed
CN-119161348-A Ibrutinib and synthesis method thereof 成都泰立贝医药技术有限公司 2024-12-20 CN claimed
CN-116130607-B Preparation method and application of solid sulfur anode 哈尔滨工业大学 2023-07-14 CN claimed
CN-116130607-A Preparation method and application of solid sulfur anode 哈尔滨工业大学 2023-05-16 CN claimed
CN-108727230-B Ibrutinib intermediate and preparation method thereof 江苏希迪制药有限公司 2021-03-23 CN claimed
WO-2017163257-A1 PROCESS FOR PREPARING PURE LH-PYRAZOLO[3,4-D] PYRIMIDINE DERIVATIVE IND-SWIFT LABORATORIES LIMITED (IN) 2017-09-28 WO claimed
EP-0314384-B1 Preparation of poly(arylene ether ketones) RAYCHEM CORP (US) 1994-02-02 EP claimed
EP-0262920-B1 PREPARATION OF ARYLENE OLIGOMERS RAYCHEM LIMITED (GB) 1993-04-07 EP claimed
EP-0178183-B1 PREPARATION OF AROMATIC KETONE-SULFONE COPOLYMERS RAYCHEM CORPORATION (a Delaware corporation) (US) 1993-01-20 EP claimed
EP-0243997-B1 PREPARATION OF POLY (ARYLENE ETHER KETONES) RAYCHEM CORPORATION (a Delaware corporation) (US) 1992-10-14 EP claimed
EP-0178183-A2 Preparation of aromatic ketone-sulfone copolymers RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP claimed
EP-0138990-A1 PREPARATION OF AROMATIC POLYMERS RAYCHEM CORPORATION (a California corporation) (US) 1985-05-02 EP claimed
EP-0124276-A2 Preparation of aromatic polymers RAYCHEM CORPORATION (a Delaware corporation) (US) 1984-11-07 EP claimed
WO-1984003892-A1 PREPARATION OF AROMATIC POLYMERS RAYCHEM CORP (US) 1984-10-11 WO claimed
WO-1984003891-A1 PREPARATION OF AROMATIC POLYMERS RAYCHEM CORP (US) 1984-10-11 WO claimed
EP-0060943-B1 PARAPHENOXYBENZOTRICHLORIDE, ITS PREPARATION AND USE OCCIDENTAL CHEMICAL CORPORATION (US) 1984-06-13 EP claimed
US-4398020-A FROM ACYL HALIDES AND HYDROCARBONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-09 US claimed
EP-0063874-A1 Production of aromatic polyketones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-11-03 EP claimed
EP-0060943-A1 Paraphenoxybenzotrichloride, its preparation and use OCCIDENTAL CHEMICAL CORPORATION (US) 1982-09-29 EP claimed
US-4268457-A Process for the preparation of paraphenoxybenzoylchloride HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-05-19 US claimed