Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | GYS1 | P13807 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23913056 | 0.90 | TBXA2R (0.35) | TBXA2RPTGER1MRGPRX4PTPN1ALOX5AP | |
| SCHEMBL21786482 | 0.89 | TBXA2R (0.37) | TBXA2RPTGER1MRGPRX4PTPN1SLC6A4 | |
| SCHEMBL21786536 | 0.89 | PTGER1 (0.41) | TBXA2RPTGER1MRGPRX4PTPN1SLC6A4 | |
| SCHEMBL22791110 | 0.87 | TBXA2R (0.36) | TBXA2RPTGER1MRGPRX4SLC6A4ALOX5AP | |
| SCHEMBL22791109 | 0.86 | CNR1 (0.37) | TBXA2RPTGER1MRGPRX4CCR5CNR1 | |
| SCHEMBL22825614 | 0.83 | STIM1 (0.35) | TBXA2RPTGER1PTPN1SLC6A4SMN1; SMN2 | |
| SCHEMBL21786441 | 0.80 | CYP19A1 (0.36) | TBXA2RPTGER1MRGPRX4PTPN1 | |
| SCHEMBL22825444 | 0.79 | PTGER1 (0.33) | TBXA2RPTGER1PTPN1SLC6A4SMN1; SMN2 | |
| SCHEMBL21786626 | 0.78 | MAPT (0.39) | MRGPRX4PTPN1GYS1SMN1; SMN2LMNA | |
| SCHEMBL21786597 | 0.77 | MAPT (0.38) | MRGPRX4SLC6A4SMN1; SMN2CCR5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046382-A1 | SUBSTITUTED HETEROCYCLES AS C-MYC TARGETING AGENTS | NORTHWESTERN UNIVERSITY (US) | 2020-03-05 | — | — | WO | disclosed |