⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787166 | 0.80 | POLB (0.35) | — | |
| SCHEMBL24913340 | 0.76 | POLB (0.36) | — | |
| SCHEMBL21786838 | 0.75 | POLB (0.37) | — | |
| SCHEMBL21786903 | 0.73 | POLG (0.35) | — | |
| SCHEMBL24913354 | 0.70 | POLG (0.46) | — | |
| SCHEMBL21786834 | 0.68 | POLG (0.40) | — | |
| SCHEMBL21786857 | 0.68 | POLB (0.42) | — | |
| SCHEMBL21786923 | 0.66 | POLB (0.43) | — | |
| SCHEMBL21786811 | 0.65 | POLG (0.47) | — | |
| SCHEMBL19662518 | 0.65 | POLB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200069717-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-03-05 | — | — | US | disclosed |