⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787388 | 0.73 | — | — | |
| SCHEMBL21787385 | 0.69 | — | — | |
| SCHEMBL21787381 | 0.69 | — | — | |
| SCHEMBL21787376 | 0.68 | — | — | |
| SCHEMBL21787369 | 0.65 | — | — | |
| SCHEMBL21787386 | 0.64 | — | — | |
| SCHEMBL10920454 | 0.63 | XIAP (0.33) | — | |
| SCHEMBL8036126 | 0.61 | — | — | |
| SCHEMBL15332258 | 0.60 | PTGER4 (0.38) | — | |
| SCHEMBL31118599 | 0.60 | PTGER4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180493-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200071318-A1 | SGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2020-03-05 | — | — | US | disclosed |