Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 1.00 |
| ▸ | BRD2 | P25440 | 1/20 | 0.64 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.64 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787849 | 1.00 | BRD4 (1.00) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL21787969 | 0.91 | BRD4 (1.00) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL24006939 | 0.91 | BRD4 (1.00) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21787966 | 0.91 | BRD4 (1.00) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21787974 | 0.91 | BRD4 (1.00) | BRD4BRD2BRD3BRDT | |
| SCHEMBL24008075 | 0.89 | BRD4 (0.87) | BRD4BRD2BRD3BRDTNPSR1 | |
| SCHEMBL21788069 | 0.89 | BRD4 (0.80) | BRD4BRD2BRD3BRDT | |
| SCHEMBL24007303 | 0.87 | BRD4 (0.80) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21787827 | 0.86 | BRD4 (0.79) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL24007728 | 0.86 | BRD4 (0.75) | BRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043821-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2020-03-05 | — | — | WO | disclosed |