Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.62 |
| ▸ | BRD2 | P25440 | 1/20 | 0.52 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.52 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787804 | 1.00 | BRD4 (0.62) | BRD4BRD2BRD3BRDTNPC1 | |
| SCHEMBL21787810 | 0.92 | BRD4 (0.73) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21787956 | 0.92 | BRD4 (0.73) | BRD4BRD2BRD3BRDT | |
| SCHEMBL24007730 | 0.86 | BRD4 (0.62) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21787872 | 0.86 | BRD4 (0.62) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21787733 | 0.86 | BRD4 (0.62) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21787801 | 0.85 | BRD4 (0.84) | BRD4BRD2BRD3BRDTNPC1 | |
| SCHEMBL24006905 | 0.83 | BRD4 (0.72) | BRD4BRD2BRD3BRDT | |
| SCHEMBL24007304 | 0.83 | BRD4 (0.72) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21788071 | 0.83 | BRD4 (0.72) | BRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043821-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2020-03-05 | — | — | WO | disclosed |