Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788902 | 0.76 | GAA (0.46) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8183692 | 0.71 | GAA (0.58) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL26710051 | 0.70 | SLC18A3 (0.61) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL1785360 | 0.70 | SLC18A3 (0.61) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL25755470 | 0.70 | SLC18A3 (0.61) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL10907426 | 0.70 | SLC18A3 (0.61) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL16311866 | 0.70 | CHRM2 (0.56) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11383894 | 0.69 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL11376280 | 0.69 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL11510177 | 0.69 | GAA (0.44) | GAACHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047447-A1 | CARDIAC SARCOMERE INHIBITORS | CYTOKINETICS, INC. (US) | 2020-03-05 | — | — | WO | disclosed |