Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21790430 | 0.92 | STING1 (0.48) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21789798 | 0.92 | STING1 (0.50) | STING1CYP3A4 | |
| SCHEMBL21766427 | 0.91 | STING1 (0.47) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21789753 | 0.88 | STING1 (0.42) | STING1 | |
| SCHEMBL30882062 | 0.87 | STING1 (0.64) | STING1CYP3A4 | |
| SCHEMBL21766137 | 0.87 | STING1 (0.64) | STING1CYP3A4 | |
| SCHEMBL21753416 | 0.85 | STING1 (0.42) | STING1 | |
| SCHEMBL21790426 | 0.84 | STING1 (0.50) | STING1CYP3A4 | |
| SCHEMBL21766411 | 0.83 | STING1 (0.62) | STING1CYP3A4 | |
| SCHEMBL21789750 | 0.82 | STING1 (0.42) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848366-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |
| WO-2020042995-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |