Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | KLK7 | P49862 | 2/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21790401 | 1.00 | MAPT (0.63) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL2512643 | 1.00 | MAPT (0.63) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL8838459 | 0.97 | MAPT (0.67) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL29401232 | 0.97 | MAPT (0.67) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL30915257 | 0.97 | MAPT (0.67) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL23161521 | 0.96 | SYK (0.65) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL2512642 | 0.96 | SYK (0.65) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL19301063 | 0.96 | SYK (0.65) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL6620798 | 0.93 | SYK (0.61) | MAPTSYKKLK7KLK5HTT | |
| SCHEMBL6619895 | 0.93 | SYK (0.61) | MAPTSYKKLK7KLK5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842437-A1 | HIGH ACTIVITY STING PROTEIN AGONIST | Adlai Nortye Biopharma Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020042995-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |
| CN-1434795-A | Acylated Pseudodipeptides with Functionalized Auxiliary Branches | OM PHARMA (CH) | 2003-08-06 | — | — | CN | disclosed |