Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19352796 | 0.88 | CPN1 (0.43) | CPN1CPB2EPHX2CCR8ALDH1A1 | |
| SCHEMBL12404022 | 0.85 | CPN1 (0.43) | CPN1CPB2EPHX2CCR8ALDH1A1 | |
| SCHEMBL21790666 | 0.82 | EPHX2 (0.50) | EPHX2ALDH1A1EPHX1DPP4 | |
| SCHEMBL21790811 | 0.78 | GAA (0.48) | EPHX2ALDH1A1THRBATML3MBTL1 | |
| SCHEMBL25018149 | 0.77 | JAK3 (0.50) | — | |
| SCHEMBL12844564 | 0.77 | CPN1 (0.47) | CPN1CPB2EPHX2CCR8ALDH1A1 | |
| SCHEMBL13866398 | 0.76 | CPN1 (0.46) | CPN1CPB2EPHX2CCR8ALDH1A1 | |
| SCHEMBL18202813 | 0.76 | CPN1 (0.49) | CPN1CPB2EPHX2CCR8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15808554 | 0.75 | CPN1 (0.45) | CPN1CPB2EPHX2CCR8ALDH1A1 | |
| SCHEMBL12404005 | 0.73 | NPC1 (0.42) | EPHX2CCR8ALDH1A1EPHX1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | CPN1 4090/4885CPB2 3934/4885EPHX2 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.