Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IL1B | P01584 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19353186 | 0.86 | GAA (0.37) | POLBGAAIL1BNLRP3KCNH2 | |
| SCHEMBL12395719 | 0.86 | GAA (0.39) | GAAIL1BNLRP3KCNH2HTR2A | |
| SCHEMBL12464694 | 0.78 | KDM4E (0.37) | POLBKDM4E | |
| SCHEMBL23133624 | 0.76 | GAA (0.41) | GAAIL1BNLRP3KDM4EDRD2 | |
| SCHEMBL10271865 | 0.76 | GAA (0.41) | GAAIL1BNLRP3KDM4EDRD2 | |
| SCHEMBL1488354 | 0.76 | GAA (0.41) | GAAIL1BNLRP3KDM4EDRD2 | |
| SCHEMBL7778206 | 0.75 | POLB (0.38) | POLBKDM4E | |
| SCHEMBL21283140 | 0.75 | POLB (0.35) | POLB | |
| SCHEMBL12464589 | 0.74 | GAA (0.40) | GAAIL1BNLRP3KCNH2KDM4E | |
| SCHEMBL1488352 | 0.74 | GAA (0.40) | GAAIL1BNLRP3KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | POLB 2240/4885GAA 4358/4885IL1B 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.