Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 20/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850524 | 0.76 | NOTUM (0.61) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21792172 | 0.68 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21776898 | 0.68 | NOTUM (0.57) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL1263960 | 0.67 | NOTUM (0.50) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL11303440 | 0.65 | NOTUM (0.53) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21792168 | 0.64 | NOTUM (0.52) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL7124314 | 0.64 | NOTUM (0.52) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL8722602 | 0.63 | NOTUM (0.50) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL24276136 | 0.63 | NOTUM (0.56) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21776979 | 0.63 | NOTUM (0.56) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043866-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2020-03-05 | — | — | WO | disclosed |