Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.79 |
| ▸ | MET | P08581 | 4/20 | 0.63 |
| ▸ | RET | P07949 | 8/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21792918 | 0.96 | KDR (0.72) | KDRMETRETEGFR | |
| SCHEMBL21792916 | 0.92 | KDR (0.68) | KDRMETRET | |
| SCHEMBL21793042 | 0.89 | KDR (0.63) | KDRMETRETEGFR | |
| SCHEMBL21265813 | 0.88 | KDR (1.00) | KDRMETRETEGFR | |
| SCHEMBL21793056 | 0.88 | RET (0.74) | KDRMETRET | |
| SCHEMBL21792959 | 0.88 | RET (0.68) | KDRMETRET | |
| SCHEMBL21793117 | 0.87 | RET (0.65) | KDRMETRET | |
| SCHEMBL21792974 | 0.87 | RET (0.65) | KDRMETRET | |
| SCHEMBL21792980 | 0.86 | RET (0.64) | KDRMETRET | |
| SCHEMBL21792917 | 0.85 | KDR (0.70) | KDRMETRETEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020042972-A1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXANE AND QUINAZOLINE OR QUINOLINE COMPOUND, COMPOSITION AND APPLICATION THEREOF | 北京赛特明强医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |