Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | EYA2 | O00167 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL2557176 | 1.00 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL840661 | 1.00 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL10639072 | 1.00 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL3391953 | 1.00 | TDP1 (0.67) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL1132175 | 0.98 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL5718746 | 0.98 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL489215 | 0.98 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL10706256 | 0.98 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL153915 | 0.94 | TDP1 (0.58) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL3391944 | 0.94 | TDP1 (0.58) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5824 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114361431-B | Process and method for regulating and controlling structure of regular micron-sized lithium carbonate material for ternary positive electrode material in lithium ion battery | 山东瑞福锂业有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118253308-A | Catalyst for continuous preparation of succinic anhydride by maleic anhydride liquid phase hydrogenation | 中国石油天然气股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-115895789-B | Universal cleaning agent for cleaning cartridge filter element of cartridge filter and online cleaning process | 华能济宁运河发电有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118147130-A | Marine microalgae DNA extracting solution and application and rapid extracting method thereof | 中国科学院海洋研究所 | 2024-06-07 | — | — | CN | claimed |
| CN-114832845-B | Composite catalyst prepared by utilizing recycled lithium battery material and preparation method thereof | 濮阳天地人环保科技股份有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117977114-A | Metal organic framework mixed modified coating and composite battery diaphragm applied by same | 广东诚刻新材料有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117878263-A | Positive electrode material, preparation method thereof and battery | 三一技术装备有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117861549-A | Positive electrode material precursor and preparation method thereof | 三一技术装备有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117766705-A | Positive electrode composite material, preparation method thereof and lithium ion battery | 深圳市德方创域新能源科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117735566-A | High-value utilization method of waste quartz crucible | 华陆工程科技有限责任公司 | 2024-03-22 | — | — | CN | claimed |
| US-20100233230-A1 | SOL-GEL NANOSTRUCTURED TITANIA RESERVOIRS FOR USE IN THE CONTROLLED RELEASE OF DRUGS IN THE CENTRAL NERVOUS SYSTEM AND METHOD OF SYNTHESIS | UNIVERSIDAD AUTONOMA (MX) | 2010-09-16 | — | — | US | claimed |
| WO-2010100107-A2 | PROCESS FOR PREPARING STABLE SUSPENSIONS OF METAL NANOPARTICLES AND THE STABLE COLLOIDAL SUSPENSIONS OBTAINED THEREBY | COLOROBBIA ITALIA S.P.A. (IT) | 2010-09-10 | — | — | WO | claimed |
| WO-2010001184-A1 | FORMULATION BASED ON MICRONIZED NATURAL CALCITE MINERAL AND MICRONIZED ZEOLITE AS AN ENHANCED PLANT BOOSTER AND MINERAL FERTILIZER | NOVATECH D.O.O. (HR) | 2010-01-07 | — | — | WO | claimed |
| EP-2020987-A1 | SOL-GEL NANOSTRUCTURED TITANIA RESERVOIRS FOR USE IN THE CONTROLLED RELEASE OF DRUGS IN THE CENTRAL NERVOUS SYSTEM AND METHOD OF SYNTHESIS | Universidad Autónoma Metropolitana (MX) | 2009-02-11 | — | — | EP | claimed |
| US-20080274066-A1 | Compositions, Methods, Devices, and Kits for Maintaining or Enhancing Tooth Whitening | BRITESMILE PROFESSIONAL, INC. | 2008-11-06 | — | — | US | claimed |
| WO-2007141590-A1 | SOL-GEL NANOSTRUCTURED TITANIA RESERVOIRS FOR USE IN THE CONTROLLED RELEASE OF DRUGS IN THE CENTRAL NERVOUS SYSTEM AND METHOD OF SYNTHESIS | UNIVERSIDAD AUTONOMA METROPOLITANA (MX) | 2007-12-13 | — | — | WO | claimed |
| CN-1800028-A | Preparation method of highly oriented transparent dihydroxy metal oxide film | UNIV BEIJING CHEMICAL (CN) | 2006-07-12 | — | — | CN | claimed |
| EP-0610694-A1 | Methyl chloroform-free desmear process in additive circuitization | International Business Machines Corporation (US) | 1994-08-17 | — | — | EP | claimed |
| US-5311660-A | Flowing heated air through printed circuit to remove solvent by gas entrainment before passing stream of oxidizing solution | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-05-17 | — | — | US | claimed |
| EP-0050733-B1 | DIAGNOSTIC DEVICE FOR FECAL OCCULT BLOOD | Memorial Hospital for Cancer and Allied Diseases (US) | 1986-06-11 | — | — | EP | claimed |