Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415820 | 0.86 | MEN1 (0.62) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL14452219 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL29499501 | 0.78 | MEN1 (1.00) | MEN1KMT2AMAPTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL22321960 | 0.77 | MEN1 (0.97) | MEN1KMT2AMAPTTDP1KDM4E | |
| Iodide SCHEMBL22542621 | 0.77 | MEN1 (0.97) | MEN1KMT2AMAPTTDP1KDM4E | |
| Iodide SCHEMBL29456898 | 0.77 | MEN1 (0.97) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL11947486 | 0.74 | MEN1 (0.64) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL4417719 | 0.72 | MEN1 (0.60) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL4422814 | 0.71 | KMT2A (0.59) | MEN1KMT2AMAPTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL4422818 | 0.71 | MEN1 (0.59) | MEN1KMT2AMAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047477-A1 | CATIONIC COMPOUNDS FOR DELIVERY OF NUCLEIC ACIDS | CITY OF HOPE (US) | 2020-03-05 | — | — | WO | disclosed |