Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.71 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179550 | 1.00 | MAPT (0.71) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL5618042 | 1.00 | MAPT (0.71) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL21457737 | 0.90 | MAPT (0.58) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL21457734 | 0.90 | MAPT (0.58) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL21457724 | 0.90 | MAPT (0.71) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL21457721 | 0.90 | MAPT (0.71) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL10719867 | 0.89 | MAPT (0.82) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL10719869 | 0.89 | MAPT (0.82) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL21457316 | 0.87 | ATM (0.57) | MAPTPDCD1CD274ALDH1A1PKM | |
| SCHEMBL21457318 | 0.87 | ATM (0.57) | MAPTPDCD1CD274ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080756-A1 | PROCESS FOR THE PREPARATION OF 1-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |