Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
| ▸ | ATF4 | P18848 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12989151 | 0.80 | CYP46A1 (0.34) | CYP46A1HRH3RIPK2MKNK1GCGR | |
| Hydrochloric Acid SCHEMBL15420647 | 0.80 | CYP46A1 (0.34) | CYP46A1HRH3RIPK2MKNK1GCGR | |
| SCHEMBL15420296 | 0.80 | CYP46A1 (0.33) | CYP46A1HRH3RIPK2MKNK1MELK | |
| SCHEMBL15420716 | 0.80 | CHRM1 (0.39) | CYP46A1HRH3RIPK2GCGRCHRM1 | |
| SCHEMBL12989171 | 0.79 | CHRM1 (0.40) | CYP46A1HRH3RIPK2GCGRCHRM1 | |
| SCHEMBL15420469 | 0.79 | CHRM1 (0.35) | CYP46A1HRH3RIPK2MKNK1GCGR | |
| SCHEMBL15420585 | 0.79 | CHRM1 (0.40) | CYP46A1HRH3RIPK2GCGRCHRM1 | |
| SCHEMBL12989178 | 0.79 | CHRM1 (0.40) | CYP46A1HRH3RIPK2GCGRCHRM1 | |
| SCHEMBL15420115 | 0.79 | CHRM1 (0.35) | CYP46A1HRH3RIPK2MKNK1GCGR | |
| SCHEMBL15420318 | 0.79 | CHRM1 (0.35) | CYP46A1HRH3RIPK2MKNK1GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | claimed |