Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.53 |
| ▸ | EP300 | Q09472 | 2/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801036 | 0.81 | BRD4 (0.57) | BRD4EP300CREBBPBRD2 | |
| SCHEMBL30335206 | 0.81 | BRD4 (0.57) | BRD4EP300CREBBPBRD2 | |
| SCHEMBL29920892 | 0.81 | BRD4 (0.55) | BRD4EP300CREBBP | |
| SCHEMBL17798085 | 0.81 | BRD4 (0.55) | BRD4EP300CREBBP | |
| SCHEMBL29920695 | 0.81 | BRD4 (0.69) | BRD4EP300CREBBP | |
| SCHEMBL16060324 | 0.81 | BRD4 (0.69) | BRD4EP300CREBBP | |
| SCHEMBL29920779 | 0.81 | BRD4 (0.57) | BRD4EP300CREBBP | |
| SCHEMBL17798083 | 0.81 | BRD4 (0.57) | BRD4EP300CREBBP | |
| SCHEMBL17797964 | 0.80 | BRD4 (0.58) | BRD4EP300CREBBPBRD2 | |
| SCHEMBL29920722 | 0.80 | BRD4 (0.58) | BRD4EP300CREBBPBRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010503-B1 | NOVEL BICYCLIC BROMODOMAIN INHIBITORS | ZENITH EPIGENETICS LTD (CA) | 2020-03-11 | — | — | EP | disclosed |