Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL19639966 | 0.99 | ELANE (0.46) | ELANEMEN1KMT2AMGAT2POLB | |
| SCHEMBL21796091 | 0.88 | ELANE (0.47) | ELANEMEN1KMT2AVNN1P2RY1 | |
| Benzene SCHEMBL19640005 | 0.88 | ELANE (0.46) | ELANEMEN1KMT2APOLBVNN1 | |
| Benzene SCHEMBL19639976 | 0.86 | ELANE (0.46) | ELANEMEN1KMT2A | |
| SCHEMBL21796099 | 0.85 | ELANE (0.45) | ELANEMEN1KMT2A | |
| Benzene SCHEMBL19640062 | 0.85 | ELANE (0.44) | ELANEMEN1KMT2A | |
| SCHEMBL21796094 | 0.84 | ELANE (0.44) | ELANE | |
| Benzene SCHEMBL19639999 | 0.84 | ELANE (0.43) | ELANE | |
| SCHEMBL21796131 | 0.83 | ELANE (0.47) | ELANEMEN1KMT2A | |
| SCHEMBL19656263 | 0.83 | ELANE (0.48) | ELANEMEN1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464268-B1 | NOVEL COMPOUNDS | CHIESI FARM SPA (IT) | 2020-03-11 | — | — | EP | claimed |