SCHEMBL2179659

SCHEMBL2179659

NC(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 3/20 0.46
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ OPRM1 P35372 2/20 0.39
▸ OPRD1 P41143 2/20 0.39
▸ OPRK1 P41145 2/20 0.39
▸ PTGS1 P23219 1/20 0.38
▸ GSTK1 Q9Y2Q3 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ PDCD1LG2 Q9BQ51 1/20 0.37
▸ CD274 Q9NZQ7 1/20 0.37
▸ ITGB2 P05107 1/20 0.37
▸ ICAM1 P05362 1/20 0.37
▸ ITGAL P20701 1/20 0.37
▸ CA2 P00918 2/20 0.35
▸ CA1 P00915 1/20 0.35
▸ NOD1 Q9Y239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8145549 1.00 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL17479551 1.00 ECE1 (0.46) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL8958919 0.99 ECE1 (0.45) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL6742594 0.97 ECE1 (0.44) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL8710506 0.96 ECE1 (0.43) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL6136428 0.96 ECE1 (0.45) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL6129713 0.96 ECE1 (0.45) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL8397119 0.96 ECE1 (0.45) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL8500636 0.96 ECE1 (0.45) ECE1MEN1KMT2AOPRM1OPRD1
SCHEMBL6129700 0.96 ECE1 (0.45) ECE1MEN1KMT2AOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 710 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1695085-A1 ENDOTOXIN DETECTION METHOD Profos AG (DE) 2006-08-30 — — EP claimed
CN-1267553-C Haemophilus transferrin receptor genes CONNAUGHT LAB (CA) 2006-08-02 — — CN claimed
WO-2005062051-A1 ENDOTOXIN DETECTION METHOD PROFOS AG (DE) 2005-07-07 — — WO claimed
CN-114380912-B Antibody therapeutics that bind CD47 株式会社柳韩洋行 2024-07-23 — — CN disclosed
CN-113754739-B Preparation method and application of coronavirus S protein RBD glycoprotein 上海君实生物医药科技股份有限公司 2024-07-05 — — CN disclosed
CN-114615881-B Triglyceride-producing non-human organisms 罗特哈姆斯泰德研究有限公司 2024-06-04 — — CN disclosed
CN-113583134-B Isolated antigen binding proteins and uses thereof 天辰生物医药(苏州)有限公司 2024-06-04 — — CN disclosed
CN-114080398-B Polypeptide dimer comprising extracellular domain of alpha subunit of IgE Fc receptor and having high sialic acid content, and pharmaceutical composition comprising same GI 医诺微新 2024-05-31 — — CN disclosed
CN-111587251-B Extracellular domain of alpha subunit of IgE Fc receptor, pharmaceutical composition comprising same and preparation method thereof GI 医诺微新 2024-05-28 — — CN disclosed
CN-110168105-B System and method for sequencing T cell receptors and uses thereof 瑞泽恩制药公司 2024-05-24 — — CN disclosed
CN-110621779-B Polypeptides having lysozyme activity, polynucleotides encoding same, uses and compositions thereof 诺维信公司 2024-05-14 — — CN disclosed
EP-0585396-A1 NOVEL $i(BACILLUS THURINGIENSIS) ISOLATES ACTIVE AGAINST HYMENOPTERAN PESTS AND GENES ENCODING HYMENOPTERAN-ACTIVE TOXINS MYCOGEN CORPORATION (US) 1994-03-09 — — EP disclosed
WO-1993021317-A1 ISOLATION, CHARACTERIZATION, AND USE OF THE HUMAN β SUBUNIT OF THE HIGH AFFINITY RECEPTOR FOR IMMUNOGLOBULIN E THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-10-28 — — WO disclosed
EP-0551329-A1 APROTININ ANALOGUES NOVO NORDISK A/S (DK) 1993-07-21 — — EP disclosed
WO-1993008693-A1 NOVEL COLEOPTERAN-ACTIVE BACILLUS THURINGIENSIS ISOLATES AND GENES ENCODING COLEOPTERAN-ACTIVE TOXINS MYCOGEN CORPORATION (US) 1993-05-13 — — WO disclosed
EP-0536350-A1 IDENTIFICATION OF A NOVEL HUMAN RECEPTOR TYROSINE KINASE GENE AMERICAN CYANAMID COMPANY (US) 1993-04-14 — — EP disclosed
WO-1992020802-A2 NOVEL BACILLUS THURINGIENSIS ISOLATES ACTIVE AGAINST HYMENOPTERAN PESTS AND GENES ENCODING HYMENOPTERAN-ACTIVE TOXINS MYCOGEN CORPORATION (US) 1992-11-26 — — WO disclosed
WO-1992014748-A1 IDENTIFICATION OF A NOVEL HUMAN RECEPTOR TYROSINE KINASE GENE AMERICAN CYANAMID COMPANY (US) 1992-09-03 — — WO disclosed
WO-1992007940-A2 BOVINE RESPIRATORY SYNCYTIAL VIRUS GENES SAMAL SIBA KUMAR (US) 1992-05-14 — — WO disclosed
WO-1992006111-A1 APROTININ ANALOGUES NOVO NORDISK A/S (DK) 1992-04-16 — — WO disclosed
Send feedback