SCHEMBL21796607

SCHEMBL21796607

Cc1ccc(-c2ccccc2C)cc1.N=C=O.N=C=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
CA1 P00915 1/20 0.50
MCL1 Q07820 1/20 0.41
TP53 P04637 2/20 0.40
NPC1 O15118 1/20 0.40
HPGDS O60760 1/20 0.40
PKM P14618 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
AGTR1 P30556 1/20 0.40
RAB9A P51151 1/20 0.40
POLB P06746 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ENPP3 O14638 1/20 0.39
ENPP1 P22413 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
GRIA1 P42261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4495660 0.88 CA12 (0.48) CA12CA2CA9CA1MCL1
SCHEMBL1047559 0.87 CA12 (0.55) CA12CA2CA9CA1MCL1
SCHEMBL29385200 0.83 TSHR (0.45) CA12CA2CA9CA1TP53
SCHEMBL160151 0.83 TSHR (0.45) CA12CA2CA9CA1TP53
SCHEMBL29703355 0.83 TSHR (0.45) CA12CA2CA9CA1TP53
SCHEMBL28586997 0.83 TSHR (0.45) CA12CA2CA9CA1TP53
SCHEMBL20986947 0.81 CA12 (0.50) CA12CA2CA9CA1MCL1
Methane SCHEMBL9069071 0.81 TSHR (0.43) CA12CA2CA9CA1TP53
Formic Acid SCHEMBL28903028 0.80 CA12 (0.50) CA12CA2CA9CA1MCL1
SCHEMBL3633054 0.80 CA12 (0.61) CA12CA2CA9CA1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239068-A1 Degradable Foam-Containing Tires, Related Methods And Kits For Adding Degradable Foam To Tires BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2024-07-18 US claimed
US-20200079039-A1 DEGRADABLE FOAM-CONTAINING TIRES, RELATED METHODS AND KITS FOR ADDING DEGRADABLE FOAM TO TIRES BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2020-03-12 US claimed
US-20240239068-A1 Degradable Foam-Containing Tires, Related Methods And Kits For Adding Degradable Foam To Tires BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2024-07-18 US disclosed
US-20230150214-A1 Degradable Foam-Containing Tires, Related Methods And Kits For Adding Degradable Foam To Tires BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2023-05-18 US disclosed
US-11559958-B2 Degradable foam-containing tires, related methods and kits for adding degradable foam to tires BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2023-01-24 US disclosed
US-20200079039-A1 DEGRADABLE FOAM-CONTAINING TIRES, RELATED METHODS AND KITS FOR ADDING DEGRADABLE FOAM TO TIRES BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2020-03-12 US disclosed