⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338109 | 0.98 | CYP2D6 (0.48) | — | |
| Hydrochloric Acid SCHEMBL2984217 | 0.98 | POLB (0.46) | — | |
| Hydrochloric Acid SCHEMBL2984220 | 0.98 | POLB (0.46) | — | |
| Hydrochloric Acid SCHEMBL5795716 | 0.98 | POLB (0.46) | — | |
| SCHEMBL8591342 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL2222378 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL8472769 | 0.91 | — | — | |
| SCHEMBL5427128 | 0.85 | CYP2D6 (0.46) | — | |
| SCHEMBL29779787 | 0.80 | — | — | |
| SCHEMBL1629420 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023712-A1 | METHOD OF REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT WITH AN ABSORBENT SOLUTION BASED ON I/II/III TRIAMINES | IFP Energies Nouvelles (FR) | 2013-01-24 | — | — | US | disclosed |
| EP-2512631-A1 | METHOD FOR REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT USING A TRIAMINE-BASED ABSORBENT SOLUTION | IFP Energies nouvelles (FR) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011080406-A1 | METHOD FOR REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT USING A TRIAMINE-BASED ABSORBENT SOLUTION | IFP Energies Nouvelles (FR) | 2011-07-07 | — | — | WO | disclosed |
| US-7829557-B2 | 2-heterosubstituted 3-aryl-4H-1-benzopyran-4-ones as novel therapeutics in breast cancer | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-11-09 | — | — | US | disclosed |
| EP-1553911-B1 | 2-HETEROSUBSTITUTED 3-ARYL-4-H-1-BENZOPYRAN-4-ONES AS NOVEL THERAPEUTICS IN BREAST CANCER | UNIV OHIO STATE RES FOUND (US) | 2010-06-23 | — | — | EP | disclosed |
| US-20090263322-A1 | OCTAHYDRO-INDOLIZINE AND QUINOLIZINE AND HEXAHYDRO-PYRROLIZINES | APODACA RICHARD | 2009-10-22 | — | — | US | disclosed |
| US-20090263322-A1 | OCTAHYDRO-INDOLIZINE AND QUINOLIZINE AND HEXAHYDRO-PYRROLIZINES | APODACA RICHARD | 2009-10-22 | — | — | US | disclosed |
| US-7592458-B2 | Dermal anesthetic compounds and pharmaceutical compositions for inducing local anesthesia and mitigating neuropathic pain | WRIGHT GEORGE E | 2009-09-22 | — | — | US | disclosed |
| US-7592458-B2 | Dermal anesthetic compounds and pharmaceutical compositions for inducing local anesthesia and mitigating neuropathic pain | WRIGHT GEORGE E | 2009-09-22 | — | — | US | disclosed |
| US-20080033052-A1 | Dermal anesthetic compounds | WRIGHT GEORGE E | 2008-02-07 | — | — | US | disclosed |
| EP-1553911-A4 | 2-HETEROSUBSTITUTED 3-ARYL-4-H-1-BENZOPYRAN-4-ONES AS NOVEL THERAPEUTICS IN BREAST CANCER | UNIV OHIO STATE RES FOUND (US) | 2006-07-26 | — | — | EP | disclosed |
| EP-1553911-A2 | 2-HETEROSUBSTITUTED 3-ARYL-4-H-1-BENZOPYRAN-4-ONES AS NOVEL THERAPEUTICS IN BREAST CANCER | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-07-20 | — | — | EP | disclosed |
| US-20040087586-A1 | 2-Heterosubstituted 3-aryl-4H-1-benzopyran-4-ones as novel therapeutics in breast cancer | US ARMY, SECRETARY OF THE ARMY | 2004-05-06 | — | — | US | disclosed |
| CN-1146542-C | Benzamide derivatives and their use as cytokine inhibitors | — | 2004-04-21 | — | — | CN | disclosed |
| WO-2004012682-A2 | 2-HETEROSUBSTITUTED 3-ARYL-4-H-1-BENZOPYRAN-4-ONES AS NOVEL THERAPEUTICS IN BREAST CANCER | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2004-02-12 | — | — | WO | disclosed |
| CN-1319092-A | Benzamide derivatives and their use as cytokine inhibitors | ASTRAZENECA AB (SE) | 2001-10-24 | — | — | CN | disclosed |
| US-4780478-A | Aminopropoxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 1988-10-25 | — | — | US | disclosed |
| US-4508732-A | Basic ethers useful as antidepressant agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-02 | — | — | US | disclosed |
| US-4376123-A | Hexahydroazepinyloxy-chromones useful as antidepressants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-03-08 | — | — | US | disclosed |
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |