Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL767521 | 0.90 | ESR1 (0.81) | ESR1 | |
| SCHEMBL767522 | 0.90 | ESR1 (0.81) | ESR1 | |
| SCHEMBL794876 | 0.90 | ESR1 (0.79) | ESR1 | |
| SCHEMBL794877 | 0.90 | ESR1 (0.79) | ESR1 | |
| SCHEMBL767429 | 0.87 | ESR1 (1.00) | ESR1 | |
| SCHEMBL767430 | 0.87 | ESR1 (1.00) | ESR1 | |
| SCHEMBL767446 | 0.87 | ESR1 (1.00) | ESR1 | |
| SCHEMBL767445 | 0.87 | ESR1 (1.00) | ESR1 | |
| SCHEMBL768230 | 0.87 | ESR1 (0.84) | ESR1 | |
| SCHEMBL768616 | 0.87 | ESR1 (0.84) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11081236-B2 | Diagnostic and therapeutic methods for the treatment of breast cancer | GENENTECH, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200082944-A1 | DIAGNOSTIC AND THERAPEUTIC METHODS FOR THE TREATMENT OF BREAST CANCER | GENENTECH, INC. | 2020-03-12 | — | — | US | disclosed |